Best Multi-Device Ergonomic Mice in 2025

A sleek ergonomic mouse sits next to a laptop on a minimalist black desk, illuminated by soft ambient light.
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@homtide
Discover the top ergonomic mice of 2025 that seamlessly connect to multiple devices, enhancing your productivity and comfort.

1

Logitech MX Master 3S

The Logitech MX Master 3S is a top ergonomic mouse with a comfy, right-handed design and quiet, precise features. It connects wirelessly, works on any surface, and boosts productivity with smart customization options.
  •  ​Comfy Fit: Soft-touch plastic, sculpted for medium to large hands, with handy thumb controls.
  •  ​Smart Features: Quiet clicks, fast Magspeed scrolling, side wheel, and gesture controls.
  •  ​Easy Connection: USB or Bluetooth, pairs with 3 devices, tracks on glass with 8000 DPI.
  •  ​Customizable: Free Logi Options+ app tweaks buttons for your workflow.
  •  ​Cross-Device: FLOW moves files between Windows and macOS effortlessly.

2

Razer Basilisk V3

The Razer Viper V3 HyperSpeed is a lightweight wireless gaming mouse designed for esports with a precise, ergonomic build. It features long battery life and advanced tech for seamless performance.
  •  ​Lightweight Build: 82g with a balanced design for smooth, consistent swipes.
  •  ​Top Sensor: Focus Pro 30K tracks accurately on any surface, even glass.
  •  Long-Lasting: Up to 280 hours of gaming on one AA battery.
  •  ​Fast Wireless: HyperSpeed offers low-latency connection and multi-device support.
  •  ​Durable Clicks: Gen-2 mechanical switches rated for 60 million clicks.

3

DELUX Wireless Silent Ergonomic Mouse

The DELUX Wireless Silent Ergonomic Mouse is a vertical mouse designed to reduce wrist strain with a comfy, natural grip. It offers silent clicks and wireless flexibility for a quiet, efficient workspace.
  •  ​Ergo Comfort: Vertical design with a handshake grip eases hand fatigue for long-term use.
  •  ​Quiet Clicks: Silent buttons cut noise by over 90%, perfect for shared or quiet spaces.
  •  ​Wireless Options: Dual-mode (Bluetooth 5.0 & 2.4G) connects easily to multiple devices.
  •  ​Adjustable DPI: Switch between 800-4000 DPI for precise control on any surface.
  •  ​Rechargeable: Built-in battery lasts up to 2 weeks, with USB-C charging while you work.

4

Logitech Lift Vertical Ergonomic Mouse

The Logitech Lift Vertical Ergonomic Mouse is a compact, upright mouse designed for small to medium right hands, promoting wrist comfort. It features quiet clicks, smart scrolling, and long-lasting wireless connectivity.
  •  ​Ergo Design: 57° vertical angle with a soft grip and thumb rest for all-day comfort.
  •  ​Quiet & Smooth: Silent clicks and a SmartWheel make scrolling seamless and discreet.
  •  ​Customizable: Easy-access buttons can be tailored to your workflow.
  •  ​Flexible Connection: Bluetooth or USB Logi Bolt works with multiple OS, up to 2 years battery.
  •  ​Eco-Friendly: Made with 54-70% recycled plastic, depending on color.

5

Kensington Ergonomic Vertical Wireless Mouse

This Ergonomic Vertical Mouse features an angled design to keep your wrist in a natural handshake position for reduced strain. It offers wireless convenience, customizable controls, and energy-saving features.
  •  ​Ergo Slope: Angled shape supports wrist and forearm comfort, with a pinky lip for smooth movement.
  •  ​Wireless Ease: 2.4GHz connection up to 33 feet with a plug-and-play USB receiver.
  •  ​Control Options: 4 buttons (left, right, forward, back) and a scroll wheel, with 800-2400 DPI settings.
  •  ​Battery Smart: Auto-sleep after 1-10 minutes of inactivity, powered by 1 AA battery with a low-battery light.
  •  ​Compact Size: 2.74" tall, 4.38" long, ideal for small to medium hands.

6

ProtoArc Ergonomic Vertical Mouse, EM11

The ProtoArc EM11 NL Vertical Bluetooth Mouse is designed for small to medium hands with an ergonomic slope to ease wrist strain. It offers multi-device connectivity, quiet clicks, and a rechargeable battery.
  •  ​Ergo Fit: Extended wrist rest for a natural grip, best for hands under 19 cm (5.43" x 2.72" x 2.67").
  •  ​Triple Connection: Dual Bluetooth 5.0 and 2.4G USB link up to 3 devices with easy switching.
  •  ​Rechargeable: 500 mAh battery with Type-C charging, sleeps after 30 mins to save power.
  •  ​Precise & Quiet: 1000-2400 DPI, silent clicks, plus forward/back buttons (not programmable, Mac-limited).
  •  ​Adjustment Note: May take 1-2 weeks to adapt to its unique ergonomic feel.

7

Logitech G502 X Plus wireless mouse

The Logitech G502 X PLUS reimagines the iconic G502 with cutting-edge gaming tech, available in black and white. It boasts fast wireless, precise sensors, and customizable features for top performance.
  •  ​Innovative Design: light force hybrid switches offer speed, reliability, and crisp clicks.
  •  ​Cool Lighting: light sync RGB with 8 LEDs adapts to play and saves battery.
  •  ​Fast & Precise: light speed wireless and HERO 25K sensor ensure pro-level accuracy.
  •  ​Custom Control: Adjustable DPI-shift button and dual-mode scroll wheel with tilt options.
  •  ​Always Charged: POWERPLAY compatibility keeps it powered wirelessly (sold separately).